Although plains settlers adopted the
plant, it remained a folk remedy until 1870. It was at this time that Dr.
H. C. F. Meyer, a patent-medicine purveyor from Pawnee City, Nebraska,
used it in his Meyer's Blood Purifier, promoting it as "an absolute cure"
for rattlesnake bites and a host of other ills. Claims like those of Dr.
Meyer gave patent medicines the name "snake oil."
In the mid-1880s, echinacea came to the attention
of researchers at the Eclectic Medical Institute in Cincinnati, a
medical school specializing in the scientific study of medicinal herbs.
After testing echinacea, the school found it to speed the healing of bee
stings, chronic nasal congestion, leg ulcers, and a variety of infections
including diphtheria, measles, chicken pox, scarlet fever, and influenza.
Word spread, and, in the days before penicillin
and modern antibiotics, the early pharmaceutical industry adopted echinacea
as an infection fighter. In fact, during the early 20th century, it would
have been hard to find a medicine cabinet that didn't hold a tincture of
echinacea.
Gradually, echinacea became a casualty of the
war between the herbally inclined Eclectic physicians and orthodox physicians.
The orthodox doctors favored the emergence of laboratory-synthesized drugs.
By World War II, as modern antibiotics became available, echinacea's popularity
waned. After 1950, it was virtually forgotten in this country.
German researchers were primarily responsible
for continuing an interest in herbal medicine. In fact, from the 1950s
through the 1980s, many studies -- almost all of them German -- showed
that echinacea had notable immune-stimulating and infection-fighting
properties. By the mid-1980s, Americans were well on their way to rediscovering
this herb. Today, echinacea is a mainstay of herbal medicine.
Echinacea is an immune stimulant. When disease-causing
germs attack the body, cells secrete compounds that attract infection-fighting
white blood cells (macrophages) to the infected area. The macrophages (literally,
"big eaters") then engulf and digest the invaders. Echinacea boosts the
macrophages' ability to destroy germs.
Echinacea also energizes other important types
of white blood cells, natural killer cells, and T-lymphocytes. The herb
also increases secretion of interleukin 1, another component of the immune
system.
The bottom line is that infections caused by viruses,
bacteria, fungi, and protozoans heal faster with echinacea than without
it.
Echinacea is most popular as a treatment for colds
and flu. By the late 1990s, more than a dozen studies had investigated
echinacea as a cold treatment. Most showed significant benefit: shorter,
milder colds. There were also studies that showed no benefit -- enough
to keep critics claiming that echinacea was worthless.
Recently, two mainstream physicians from the University
of Wisconsin at Madison, together with a naturopath at Bastyr University
(the naturopathic medical school near Seattle), analyzed every published
study of echinacea for both the prevention and treatment of colds
and flu.
For treatment of the common cold and flu, the
researchers analyzed eight studies involving more than 1,000 participants.
The trials were double-blind, meaning that some subjects received a placebo
while the rest took echinacea. Those who used the herb took it in various
preparations -- tablets, capsules, juice, or tincture -- and the preparations
used all the immune-boosting parts of the plant: the root, leaves, and
flowers.
All eight studies showed benefit. Six of the studies
were statistically significant; two were not, but they showed a clear trend
in the direction of benefit. Compared to untreated cold sufferers, the
herb produced an average 50 percent reduction in symptom severity and a
similar reduction in the number of days the subjects felt ill. The researchers
concluded that echinacea does speed the treatment of the common cold.
Commission E, the German counterpart of the Food
and Drug Administration, is an expert panel responsible for judging the
safety and effectiveness of herbal medicines. They endorse echinacea as
a treatment for colds and flu.
With regard to prevention, the researchers analyzed
four studies with a total of 1,152 participants. Again, the trials were
double-blind and used various preparations of all parts of the plant. None
of these studies showed statistically significant preventive value. Based
on this information, the reviewers' concluded that echinacea does not help
prevent colds or flu.
It should be noted that traditional herbalists
have never recommended echinacea as a preventive measure, only as a treatment
for infectious illnesses.
In the cold-treatment studies that showed the
most benefit, participants began taking echinacea as soon as they felt
the first twinges of a cold or flu coming on. It was taken several times
a day when symptoms were worse, and less often when there was noted improvement.
Finally, echinacea has been shown to help treat
recurrent vaginal yeast infections. In a German study, 203 women with these
annoying infections were treated with either a standard pharmaceutical
anti-yeast cream or the cream supplemented by oral doses of echinacea.
After six months, 60 percent of the women treated with the antifungal cream
alone experienced recurrences. Among those also treated with the echinacea
supplement, the figure was only 16 percent, a highly significant difference.